Read individual product descriptions for a more comprehensive analysis of the respective compounds, but this particular combination works synergistically to add substantial amounts of bodyweight.
MK-677 increases IGF-1 production, which substantially increases the body’s sensitivity to androgenic activity.
S-23, as a selective androgen receptor modulator, is therefore significantly more effective when combined with MK-677.
The effect of the S-23 is aided by the effect MK-677 has on ghrelin production. With the corresponding increase in hunger and consumption of additional calories, weight gain is inevitable.
The RAD-140 is anabolic without being androgenic, exploring multiple growth pathway is always preferable to and more effective than overdosing any one of them. The RAD-140 lowers SHBG and modulates the expression of the ESR1 gene, the net effect is reduced estrogenic binding affinity and a tighter/fuller look.
YK-11 is a myostatin-inhibtor. The best way to think about it is a compound that raises the upper ceiling limit to growth. It functions more like a synthetic DHT than a selective androgen receptor modulator, and it is quite unique in its mechanism of action. Expect an increase in lean muscle mass and strength.