It should be noted that yohimbine’s efficacy is limited in the presence of insulin, so eating before using it is not recommended. For those fasted cardio diehards this is a great stack to boost endurance and target stubborn visceral fat stores. It will improve the rate at which you oxidise fat for energy, it will significantly boost cardiovascular endurance and leave you feeling charged up for your day. This is because yohimbine is an adrenergenic beta-agonist which upregulates norepinephrine release. Remember that yohimbine is also anti-duiretic in its effect, so to realise the fat loss it is recommended to cycle off for a week every two weeks. In this time subcutaneous water retention levels will drop significantly.